Loading...

The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation

Mitochondrial RNA polymerases depend on initiation factors, such as TFB2M in humans and Mtf1 in yeast Saccharomyces cerevisiae, for promoter-specific transcription. These factors drive the melting of promoter DNA, but how they support RNA priming and growth was not understood. We show that the flexi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Basu, Urmimala, Lee, Seung-Won, Deshpande, Aishwarya, Shen, Jiayu, Sohn, Byeong-Kwon, Cho, Hayoon, Kim, Hajin, Patel, Smita S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049685/
https://ncbi.nlm.nih.gov/pubmed/31980825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa040
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!