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The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation

Mitochondrial RNA polymerases depend on initiation factors, such as TFB2M in humans and Mtf1 in yeast Saccharomyces cerevisiae, for promoter-specific transcription. These factors drive the melting of promoter DNA, but how they support RNA priming and growth was not understood. We show that the flexi...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Basu, Urmimala, Lee, Seung-Won, Deshpande, Aishwarya, Shen, Jiayu, Sohn, Byeong-Kwon, Cho, Hayoon, Kim, Hajin, Patel, Smita S
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049685/
https://ncbi.nlm.nih.gov/pubmed/31980825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa040
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