FoxO1–Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth

Forkhead box O (FoxO) proteins and thyroid hormone (TH) have well established roles in cardiovascular morphogenesis and remodeling. However, specific role(s) of individual FoxO family members in stress-induced growth and remodeling of cardiomyocytes remains unknown. Here, we report that FoxO1, but n...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Ferdous, Anwarul, Wang, Zhao V., Luo, Yuxuan, Li, Dan L., Luo, Xiang, Schiattarella, Gabriele G., Altamirano, Francisco, May, Herman I., Battiprolu, Pavan K., Nguyen, Annie, Rothermel, Beverly A., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242347/
https://ncbi.nlm.nih.gov/pubmed/32439985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16345-y
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