FoxO1–Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth

Forkhead box O (FoxO) proteins and thyroid hormone (TH) have well established roles in cardiovascular morphogenesis and remodeling. However, specific role(s) of individual FoxO family members in stress-induced growth and remodeling of cardiomyocytes remains unknown. Here, we report that FoxO1, but n...

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Vydáno v:Nat Commun
Hlavní autoři: Ferdous, Anwarul, Wang, Zhao V., Luo, Yuxuan, Li, Dan L., Luo, Xiang, Schiattarella, Gabriele G., Altamirano, Francisco, May, Herman I., Battiprolu, Pavan K., Nguyen, Annie, Rothermel, Beverly A., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242347/
https://ncbi.nlm.nih.gov/pubmed/32439985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16345-y
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