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FoxO1–Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth

Forkhead box O (FoxO) proteins and thyroid hormone (TH) have well established roles in cardiovascular morphogenesis and remodeling. However, specific role(s) of individual FoxO family members in stress-induced growth and remodeling of cardiomyocytes remains unknown. Here, we report that FoxO1, but n...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ferdous, Anwarul, Wang, Zhao V., Luo, Yuxuan, Li, Dan L., Luo, Xiang, Schiattarella, Gabriele G., Altamirano, Francisco, May, Herman I., Battiprolu, Pavan K., Nguyen, Annie, Rothermel, Beverly A., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242347/
https://ncbi.nlm.nih.gov/pubmed/32439985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16345-y
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