Metabolic stress–induced activation of FoxO1 triggers diabetic cardiomyopathy in mice

The leading cause of death in diabetic patients is cardiovascular disease; diabetic cardiomyopathy is typified by alterations in cardiac morphology and function, independent of hypertension or coronary disease. However, the molecular mechanism that links diabetes to cardiomyopathy is incompletely un...

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Detalhes bibliográficos
Main Authors: Battiprolu, Pavan K., Hojayev, Berdymammet, Jiang, Nan, Wang, Zhao V., Luo, Xiang, Iglewski, Myriam, Shelton, John M., Gerard, Robert D., Rothermel, Beverly A., Gillette, Thomas G., Lavandero, Sergio, Hill, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287230/
https://ncbi.nlm.nih.gov/pubmed/22326951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60329
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