Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes

More effective treatments for diabetic nephropathy remain a major unmet clinical need. Increased oxidative stress is one of the most important pathological mechanisms that lead to kidney damage and functional impairment induced by diabetes. Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Locatelli, Monica, Zoja, Carlamaria, Zanchi, Cristina, Corna, Daniela, Villa, Sebastian, Bolognini, Silvia, Novelli, Rubina, Perico, Luca, Remuzzi, Giuseppe, Benigni, Ariela, Cassis, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242337/
https://ncbi.nlm.nih.gov/pubmed/32439965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65423-0
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