Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing

Alternative mRNA splicing increases protein diversity, and alternative splicing events (ASEs) drive oncogenesis in multiple tumor types. However, the driving alterations that underlie the broad dysregulation of ASEs are incompletely defined. Using head and neck squamous cell carcinoma (HNSCC) as a m...

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Veröffentlicht in:PLoS One
Hauptverfasser: Sakai, Akihiro, Ando, Mizuo, Fukusumi, Takahito, Ren, Shuling, Liu, Chao, Qualliotine, Jesse, Haft, Sunny, Sadat, Sayed, Saito, Yuki, Guo, Theresa W., Xu, Guorong, Sasik, Roman, Fisch, Kathleen M., Gutkind, J. Silvio, Fertig, Elana J., Molinolo, Alfredo A., Califano, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241804/
https://ncbi.nlm.nih.gov/pubmed/32437477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233380
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