Mutation of Chromatin Regulators and Focal Hotspot Alterations Characterize HPV Positive Oropharyngeal Squamous Cell Carcinoma

BACKGROUND: HPV associated oropharyngeal cancer is a clinically and biologically distinct disease from smoking related Head and Neck Squamous Cell Carcinoma (HNSCC). Despite its rapidly increasing incidence, the mutational landscape of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) remai...

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Veröffentlicht in:Cancer
Hauptverfasser: Haft, Sunny, Ren, Shuling, Xu, Guorong, Mark, Adam, Fisch, Kathleen, Guo, Theresa W, Khan, Zubair, Pang, John, Ando, Mizuo, Liu, Chao, Sakai, Akihiro, Fukusumi, Takahito, Califano, Joseph A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602825/
https://ncbi.nlm.nih.gov/pubmed/30933315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32068
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