Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials

In 2014, our research network was involved in the evaluation of favipiravir, an anti‐influenza polymerase inhibitor, against Ebola virus. In this review, we discuss how mathematical modeling was used, first to propose a relevant dosing regimen in humans, and then to optimize its antiviral efficacy i...

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Sparad:
Bibliografiska uppgifter
I publikationen:CPT Pharmacometrics Syst Pharmacol
Huvudupphovsmän: Madelain, Vincent, Mentré, France, Baize, Sylvain, Anglaret, Xavier, Laouénan, Cédric, Oestereich, Lisa, Nguyen, Thi Huyen Tram, Malvy, Denis, Piorkowski, Géraldine, Graw, Frederik, Günther, Stephan, Raoul, Hervé, de Lamballerie, Xavier, Guedj, Jérémie
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239338/
https://ncbi.nlm.nih.gov/pubmed/32198838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12510
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