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Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood

OBJECTIVE: Pregnancy-associated plasma protein-A2 (PAPP-A2) is a metalloproteinase that cleaves IGFBP-3 and IGFBP-5. Human mutations in PAPPA2 result in short stature with a low percentage of free IGF-I. Little is known about PAPP-A2 levels and the regulation of free IGF-I throughout childhood. We e...

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Detalhes bibliográficos
Publicado no:Eur J Endocrinol
Main Authors: Fujimoto, Masanobu, Khoury, Jane C, Khoury, Philip R, Kalra, Bhanu, Kumar, Ajay, Sluss, Patrick, Oxvig, Claus, Hwa, Vivian, Dauber, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238294/
https://ncbi.nlm.nih.gov/pubmed/31961798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-19-0859
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