Loading...

Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents

[Image: see text] Sigma receptors (SRs) are recognized as valuable targets for the treatment of neurodegenerative disorders. A series of novel SRs ligands were designed by combining key pharmacophoric amines (i.e., benzylpiperidine or benzylpiperazine) with new 1,3-dithiolane-based heterocycles and...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Franchini, Silvia, Linciano, Pasquale, Puja, Giulia, Tait, Annalisa, Borsari, Chiara, Denora, Nunzio, Iacobazzi, Rosa Maria, Brasili, Livio, Sorbi, Claudia
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236556/
https://ncbi.nlm.nih.gov/pubmed/32435421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00129
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!