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Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site
To investigate the modulatory effects of sigma ligands on the N-methyl- D-aspartate (NMDA) receptor-ion channel complex in vivo, we examined the intact cell binding of 3H-N-[1-(2-thienyl)cyclohexyl]piperidine (3H- TCP) to cultured neuronal cells prepared from fetal rat telencephalon. The 3H-TCP bind...
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| 發表在: | J Neurosci |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
1995
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6578269/ https://ncbi.nlm.nih.gov/pubmed/7529831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-01-00731.1995 |
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