Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma

Intratumor heterogeneity (ITH) of genomic alterations may impact prognosis of lung adenocarcinoma (LUAD). Here, we investigate ITH of somatic copy number alterations (SCNAs), DNA methylation, and point mutations in lung cancer driver genes in 292 tumor samples from 84 patients with LUAD. LUAD sample...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Hua, Xing, Zhao, Wei, Pesatori, Angela C., Consonni, Dario, Caporaso, Neil E., Zhang, Tongwu, Zhu, Bin, Wang, Mingyi, Jones, Kristine, Hicks, Belynda, Song, Lei, Sampson, Joshua, Wedge, David C., Shi, Jianxin, Landi, Maria Teresa
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235245/
https://ncbi.nlm.nih.gov/pubmed/32424208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16295-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky