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Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma
Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. Promoter methylation status of the DNA repair enzyme O(6)-methylguanine DNA methyltransferase (MGMT) is the most important clinical biomarker in...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778014/ https://ncbi.nlm.nih.gov/pubmed/26940435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22477 |
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