Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma

Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. Promoter methylation status of the DNA repair enzyme O(6)-methylguanine DNA methyltransferase (MGMT) is the most important clinical biomarker in...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Parker, Nicole R., Hudson, Amanda L., Khong, Peter, Parkinson, Jonathon F., Dwight, Trisha, Ikin, Rowan J., Zhu, Ying, Cheng, Zhangkai Jason, Vafaee, Fatemeh, Chen, Jason, Wheeler, Helen R., Howell, Viive M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778014/
https://ncbi.nlm.nih.gov/pubmed/26940435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22477
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi