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O11.3. SYNAPTIC MARKER PROTEIN SV2A IS REDUCED IN SCHIZOPHRENIA IN VIVO AND UNAFFECTED BY ANTIPSYCHOTICS IN RATS

BACKGROUND: The synaptic dysfunction hypothesis of schizophrenia is supported by multiple lines of evidence. However, in vivo evidence is lacking. Moreover, it is not known if antipsychotics alter synaptic protein levels. We addressed this in a combined clinical study using [11C]UCB-J, a positron em...

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Bibliografische gegevens
Gepubliceerd in:Schizophr Bull
Hoofdauteurs: Chika Onwordi, Ellis, Halff, Els, Whitehurst, Thomas, Mansur, Ayla, Cotel, Marie-Caroline, Wells, Lisa, Creeney, Hannah, Bonsall, David, Rogdaki, Maria, Shatalina, Ekaterina, Reis Marques, Tiago, Rabiner, Eugenii, Gunn, Roger, Natesan, Sridhar, Vernon, Anthony, Howes, Oliver D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233999/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbaa028.063
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