O11.3. SYNAPTIC MARKER PROTEIN SV2A IS REDUCED IN SCHIZOPHRENIA IN VIVO AND UNAFFECTED BY ANTIPSYCHOTICS IN RATS

BACKGROUND: The synaptic dysfunction hypothesis of schizophrenia is supported by multiple lines of evidence. However, in vivo evidence is lacking. Moreover, it is not known if antipsychotics alter synaptic protein levels. We addressed this in a combined clinical study using [11C]UCB-J, a positron em...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Chika Onwordi, Ellis, Halff, Els, Whitehurst, Thomas, Mansur, Ayla, Cotel, Marie-Caroline, Wells, Lisa, Creeney, Hannah, Bonsall, David, Rogdaki, Maria, Shatalina, Ekaterina, Reis Marques, Tiago, Rabiner, Eugenii, Gunn, Roger, Natesan, Sridhar, Vernon, Anthony, Howes, Oliver D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Oral Session: Digital Health/Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233999/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbaa028.063
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