S31. ENHANCEMENT OF SYNAPTIC PLASTICITY BY COMBINATION OF PDE2 AND PDE9 INHIBITION PRESUMABLY VIA PRE- AND POST-SYNAPTIC MECHANISMS

BACKGROUND: Evidence from clinical and preclinical studies has led to the hypothesis that impaired glutamatergic transmission and NMDA receptor hypofunction play an important role in cognitive impairment associated with schizophrenia (CIAS). Second messenger pathways depending on cAMP and/or cGMP ar...

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Dades bibliogràfiques
Publicat a:Schizophr Bull
Autors principals: Rosenbrock, Holger, Kroker, Katja, Stierstorfer, Birgit, Hobson, Scott, Arban, Roberto, Dorner-Ciossek, Cornelia
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Poster Session I
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233945/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbaa031.097
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