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Targeting the dopamine D(1) receptor or its downstream signalling by inhibiting phosphodiesterase‐1 improves cognitive performance
BACKGROUND AND PURPOSE: Insufficient prefrontal dopamine 1 (D(1)) receptor signalling has been linked to cognitive dysfunction in several psychiatric conditions. Because the PDE1 isoform B (PDE1B) is postulated to regulate D(1) receptor‐dependent signal transduction, in this study we aimed to elucid...
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| Pubblicato in: | Br J Pharmacol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016630/ https://ncbi.nlm.nih.gov/pubmed/29726015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14350 |
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