S141. TRANSGENIC OVEREXPRESSION OF THE TYPE III ISOFORM OF NEUREGULIN 1 IN MICE INDUCES ABNORMALITIES ON AUDITORY EVENT RELATED EEG BIOMARKERS RELATED TO SCHIZOPHRENIA

BACKGROUND: Genetic, post-mortem and preclinical studies in transgenic mice repeatedly implicate neuregulin 1 (NRG1) as a critical component in the pathophysiology of schizophrenia. Its predominant neuronal receptor, ErbB4, is primarily expressed in fast-spiking interneurons enabling the maintenance...

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Publié dans:Schizophr Bull
Auteurs principaux: Rosenbrock, Holger, Nissen, Wiebke, Arban, Roberto, Moritz, Rossner, Markus, Schwab, Dorner-Ciossek, Cornelia, Schülert, Niklas
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887550/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby018.928
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