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F21. THE PHOSPHODIESTERASE-9 INHIBITOR BI 409306 ATTENUATES SOCIAL INTERACTION AND DOPAMINERGIC DEFICITS IN ADULT OFFSPRING OF POLY(I:C)-BASED MATERNAL IMMUNE ACTIVATION NEURODEVELOPMENTAL MOUSE MODEL
BACKGROUND: Rodent models of maternal immune activation (MIA) are used as an experimental approach for neurodevelopmental disorders such as schizophrenia to study neuronal and behavioral dysfunctions of offspring. In particular, injection of the viral mimic poly(I:C) in pregnant mice causes disrupti...
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| Publié dans: | Schizophr Bull |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6455403/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz018.433 |
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