Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling

Rationale: Vascular remodeling, including smooth muscle cell hypertrophy and proliferation, is the key pathological feature of pulmonary arterial hypertension (PAH). Prostaglandin I(2) analogs (beraprost, iloprost, and treprostinil) are effective in the treatment of PAH. Of note, the clinically favo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: He, Yuhu, Zuo, Caojian, Jia, Daile, Bai, Peiyuan, Kong, Deping, Chen, Di, Liu, Guizhu, Li, Juanjuan, Wang, Yuanyang, Chen, Guilin, Yan, Shuai, Xiao, Bing, Zhang, Jian, Piao, Lingjuan, Li, Yanli, Deng, Yi, Li, Bin, Roux, Philippe P., Andreasson, Katrin I., Breyer, Richard M., Su, Yunchao, Wang, Jian, Lyu, Ankang, Shen, Yujun, Yu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233340/
https://ncbi.nlm.nih.gov/pubmed/31917615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201911-2137OC
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados