Tregs-derived interleukin 35 attenuates endothelial proliferation through STAT1 in pulmonary hypertension

BACKGROUND: To explore the source, the role and the specific mechanism of IL-35 and its downstream molecules in the development of pulmonary hypertension. METHODS: 8–10 weeks male mice were undergoing hypoxia combined with SU5416 (HySu) to establish a pulmonary hypertension (PH) model. The phenotype...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Ann Transl Med
Hauptverfasser: Wan, Naifu, Rong, Wuwei, Zhu, Wentong, Jia, Daile, Bai, Peiyuan, Liu, Guizhu, Wan, Qiangyou, Lyu, Ankang
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2021
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263866/
https://ncbi.nlm.nih.gov/pubmed/34350241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-21-1952
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge