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The interaction between RUNX2 and core binding factor beta (CBFβ) as a potential therapeutic target in canine osteosarcoma

Osteosarcoma remains the most common primary bone tumor in dogs with half of affected dogs unable to survive one year beyond diagnosis. New therapeutic options are needed to improve outcomes for this disease. Recent investigations into potential therapeutic targets have focused on cell surface molec...

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Detalhes bibliográficos
Publicado no:Vet Comp Oncol
Main Authors: Alegre, Fernando, Ormonde, Amanda R., Godinez, Dayn R., Illendula, Anuradha, Bushweller, John H., Wittenburg, Luke A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233265/
https://ncbi.nlm.nih.gov/pubmed/31381810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12526
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