The interaction between RUNX2 and core binding factor beta (CBFβ) as a potential therapeutic target in canine osteosarcoma

Osteosarcoma remains the most common primary bone tumor in dogs with half of affected dogs unable to survive one year beyond diagnosis. New therapeutic options are needed to improve outcomes for this disease. Recent investigations into potential therapeutic targets have focused on cell surface molec...

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Publicado en:Vet Comp Oncol
Autores principales: Alegre, Fernando, Ormonde, Amanda R., Godinez, Dayn R., Illendula, Anuradha, Bushweller, John H., Wittenburg, Luke A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233265/
https://ncbi.nlm.nih.gov/pubmed/31381810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12526
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