Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking

RUNX1 has recently been shown to play an important role in determination of mammary epithelial cell identity. However, mechanisms by which loss of the RUNX1 transcription factor in mammary epithelial cells leads to epithelial-to-mesenchymal transition (EMT) are not known. Here, we report that intera...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rose, Joshua T., Moskovitz, Eliana, Boyd, Joseph R., Gordon, Jonathan A., Bouffard, Nicole A., Fritz, Andrew J., Illendula, Anuradha, Bushweller, John H., Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335667/
https://ncbi.nlm.nih.gov/pubmed/32655837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27637
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