2′, 5′-Oligoadenylate Synthetase 2 (OAS2) Inhibits Zika Virus Replication through Activation of Type Ι IFN Signaling Pathway

Background: 2′, 5′-oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore the effect of OAS2 on ZIKV replication and its underlying mechanism....

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Veröffentlicht in:Viruses
Hauptverfasser: Liao, Xinzhong, Xie, He, Li, Shilin, Ye, Haiyan, Li, Shuang, Ren, Kai, Li, Yujia, Xu, Min, Lin, Wenyu, Duan, Xiaoqiong, Yang, Chunhui, Chen, Limin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232345/
https://ncbi.nlm.nih.gov/pubmed/32276512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040418
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