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2′, 5′-Oligoadenylate Synthetase 2 (OAS2) Inhibits Zika Virus Replication through Activation of Type Ι IFN Signaling Pathway

Background: 2′, 5′-oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore the effect of OAS2 on ZIKV replication and its underlying mechanism....

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Liao, Xinzhong, Xie, He, Li, Shilin, Ye, Haiyan, Li, Shuang, Ren, Kai, Li, Yujia, Xu, Min, Lin, Wenyu, Duan, Xiaoqiong, Yang, Chunhui, Chen, Limin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232345/
https://ncbi.nlm.nih.gov/pubmed/32276512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040418
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