2′, 5′-Oligoadenylate Synthetase 2 (OAS2) Inhibits Zika Virus Replication through Activation of Type Ι IFN Signaling Pathway

Background: 2′, 5′-oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore the effect of OAS2 on ZIKV replication and its underlying mechanism....

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Liao, Xinzhong, Xie, He, Li, Shilin, Ye, Haiyan, Li, Shuang, Ren, Kai, Li, Yujia, Xu, Min, Lin, Wenyu, Duan, Xiaoqiong, Yang, Chunhui, Chen, Limin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232345/
https://ncbi.nlm.nih.gov/pubmed/32276512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040418
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