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Toxoplasma GRA15 limits parasite growth in IFNγ‐activated fibroblasts through TRAF ubiquitin ligases

The protozoan parasite Toxoplasma gondii lives inside a vacuole in the host cytosol where it is protected from host cytoplasmic innate immune responses. However, IFNγ‐dependent cell‐autonomous immunity can destroy the vacuole and the parasite inside. Toxoplasma strain differences in susceptibility t...

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Foilsithe in:EMBO J
Main Authors: Mukhopadhyay, Debanjan, Sangaré, Lamba Omar, Braun, Laurence, Hakimi, Mohamed‐Ali, Saeij, Jeroen PJ
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232000/
https://ncbi.nlm.nih.gov/pubmed/32293748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103758
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