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Toxoplasma GRA15 limits parasite growth in IFNγ‐activated fibroblasts through TRAF ubiquitin ligases

The protozoan parasite Toxoplasma gondii lives inside a vacuole in the host cytosol where it is protected from host cytoplasmic innate immune responses. However, IFNγ‐dependent cell‐autonomous immunity can destroy the vacuole and the parasite inside. Toxoplasma strain differences in susceptibility t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Mukhopadhyay, Debanjan, Sangaré, Lamba Omar, Braun, Laurence, Hakimi, Mohamed‐Ali, Saeij, Jeroen PJ
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232000/
https://ncbi.nlm.nih.gov/pubmed/32293748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103758
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