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Toxoplasma GRA15 limits parasite growth in IFNγ‐activated fibroblasts through TRAF ubiquitin ligases

The protozoan parasite Toxoplasma gondii lives inside a vacuole in the host cytosol where it is protected from host cytoplasmic innate immune responses. However, IFNγ‐dependent cell‐autonomous immunity can destroy the vacuole and the parasite inside. Toxoplasma strain differences in susceptibility t...

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Bibliographic Details
Published in:EMBO J
Main Authors: Mukhopadhyay, Debanjan, Sangaré, Lamba Omar, Braun, Laurence, Hakimi, Mohamed‐Ali, Saeij, Jeroen PJ
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232000/
https://ncbi.nlm.nih.gov/pubmed/32293748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103758
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