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Small Conformational Changes Underlie Evolution of Resistance to NNRTI in HIV Reverse Transcriptase

Despite achieving considerable success in reducing the number of fatalities due to acquired immunodeficiency syndrome, emergence of resistance against the reverse transcriptase (RT) inhibitor drugs remains one of the biggest challenges of the human immunodeficiency virus antiretroviral therapy (ART)...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Srivastava, Ashutosh, Birari, Varun, Sinha, Somdatta
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231925/
https://ncbi.nlm.nih.gov/pubmed/32348721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.008
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