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Blood Outgrowth Endothelial Cells as a Cellular Carrier for Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Preclinical Models of Non-Small Cell Lung Cancer

Oncolytic viruses have demonstrated efficacy in numerous tumor models including non-small cell lung cancer (NSCLC). One limitation of viral therapy for metastatic lung cancer is that systemic administration can be hindered by complement and antiviral immunity. Thus, we investigated whether ex vivo-i...

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Publicat a:Transl Oncol
Autors principals: Patel, Manish R., Jacobson, Blake A., Ji, Yan, Hebbel, Robert P., Kratzke, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231872/
https://ncbi.nlm.nih.gov/pubmed/32422574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100782
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