Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Vesicular stomatitis virus (VSV) is a potent oncolytic virus for many tumors. VSV that produces interferon-β (VSV-IFNβ) is now in early clinical testing for solid tumors. Here, the preclinical activity of VSV and VSV-IFNβ against non-small cell lung cancer (NSCLC) is reported. NSCLC cell lines were...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Patel, Manish R., Jacobson, Blake A., Ji, Yan, Drees, Jeremy, Tang, Shaogeng, Xiong, Kerry, Wang, Hengbing, Prigge, Jennifer E., Dash, Alexander S., Kratzke, Andrea K., Mesev, Emily, Etchison, Ryan, Federspiel, Mark J., Russell, Stephen J., Kratzke, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741756/
https://ncbi.nlm.nih.gov/pubmed/26431376
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