Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Vesicular stomatitis virus (VSV) is a potent oncolytic virus for many tumors. VSV that produces interferon-β (VSV-IFNβ) is now in early clinical testing for solid tumors. Here, the preclinical activity of VSV and VSV-IFNβ against non-small cell lung cancer (NSCLC) is reported. NSCLC cell lines were...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Patel, Manish R., Jacobson, Blake A., Ji, Yan, Drees, Jeremy, Tang, Shaogeng, Xiong, Kerry, Wang, Hengbing, Prigge, Jennifer E., Dash, Alexander S., Kratzke, Andrea K., Mesev, Emily, Etchison, Ryan, Federspiel, Mark J., Russell, Stephen J., Kratzke, Robert A.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741756/
https://ncbi.nlm.nih.gov/pubmed/26431376
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