Blood Outgrowth Endothelial Cells as a Cellular Carrier for Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Preclinical Models of Non-Small Cell Lung Cancer

Oncolytic viruses have demonstrated efficacy in numerous tumor models including non-small cell lung cancer (NSCLC). One limitation of viral therapy for metastatic lung cancer is that systemic administration can be hindered by complement and antiviral immunity. Thus, we investigated whether ex vivo-i...

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Опубликовано в: :Transl Oncol
Главные авторы: Patel, Manish R., Jacobson, Blake A., Ji, Yan, Hebbel, Robert P., Kratzke, Robert A.
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press 2020
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Original article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231872/
https://ncbi.nlm.nih.gov/pubmed/32422574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100782
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