RESISTANCE OF PANCREATIC CANCER CELLS TO ONCOLYTIC VESICULAR STOMATITIS VIRUS: ROLE OF TYPE I INTERFERON SIGNALING

Oncolytic virus (OV) therapy takes advantage of common cancer characteristics, such as defective type I interferon (IFN) signaling, to preferentially infect and kill cancer cells with viruses. Our recent study (Murphy et al., 2012, J. Virol., 86: 3073-87) found human pancreatic ductal adenocarcinoma...

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Autors principals: Moerdyk-Schauwecker, Megan, Shah, Nirav R., Murphy, Andrea M., Hastie, Eric, Mukherjee, Pinku, Grdzelishvili, Valery Z.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544977/
https://ncbi.nlm.nih.gov/pubmed/23246628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.11.014
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