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DNA Polymerase theta (Polθ) – an error-prone polymerase necessary for genome stability
Mammalian cells have evolved multiple pathways to repair DNA double strand breaks (DSBs) and ensure genome stability. In addition to non-homologous end-joining (NHEJ) and homologous recombination (HR), cells evolved an error-prone repair pathway termed microhomology-mediated end joining (MMEJ). The...
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| Publicado no: | Curr Opin Genet Dev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7230004/ https://ncbi.nlm.nih.gov/pubmed/32302896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.02.017 |
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