Cargando...
Error-prone replication through UV lesions by DNA polymerase θ protects against skin cancers
Cancers from sun-exposed skin accumulate “driver” mutations, causally implicated in oncogenesis. Since errors incorporated during translesion synthesis (TLS) opposite UV lesions would generate these mutations, TLS mechanisms are presumed to underlie cancer development. To address the role of TLS in...
Guardado en:
| Publicado en: | Cell |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6453116/ https://ncbi.nlm.nih.gov/pubmed/30773314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.01.023 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|