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Biosynthetic Incorporation of Site-Specific Isotopes in β-Lactam Antibiotics Enables Biophysical Studies

A biophysical understanding of the mechanistic, chemical, and physical origins underlying antibiotic action and resistance is vital to the discovery of novel therapeutics and the development of strategies to combat the growing emergence of antibiotic resistance. The site-specific introduction of sta...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Kozuch, Jacek, Schneider, Samuel H., Boxer, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229998/
https://ncbi.nlm.nih.gov/pubmed/32175720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b01054
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