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Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition

A correlation between histone acetylation and transcription has been noted for a long time, but little is known about what step(s) in the transcription cycle is influenced by acetylation. We have examined the immediate transcriptional response to histone deacetylase (HDAC) inhibition, and find that...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Vaid, Roshan, Wen, Jiayu, Mannervik, Mattias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229826/
https://ncbi.nlm.nih.gov/pubmed/32297950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa234
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