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Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition

A correlation between histone acetylation and transcription has been noted for a long time, but little is known about what step(s) in the transcription cycle is influenced by acetylation. We have examined the immediate transcriptional response to histone deacetylase (HDAC) inhibition, and find that...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Vaid, Roshan, Wen, Jiayu, Mannervik, Mattias
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229826/
https://ncbi.nlm.nih.gov/pubmed/32297950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa234
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