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The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth

High-mobility group AT-hook 2 (HMGA2) is an architectural transcription factor that plays essential roles in embryonic development and cancer progression. However, the mechanism of HMGA2 regulation remains largely uncharacterized. Here, we demonstrate that HMGA2 can be modulated by hepatitis B X-int...

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Publicado en:Nucleic Acids Res
Main Authors: Wu, Yue, Wang, Xue, Xu, Feifei, Zhang, Lu, Wang, Tianjiao, Fu, Xueli, Jin, Tianzhi, Zhang, Weiying, Ye, Lihong
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229824/
https://ncbi.nlm.nih.gov/pubmed/32313942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa232
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