PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6

HOXB9 is a homeobox domain-containing transcription factor, playing an important role in embryonic development and cancer progression. However, the precise post-translational modifications (PTMs) of HOXB9 and the corresponding roles are unclear. Here, we report that acetyltransferase p300/CBP-associ...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wan, Junhu, Xu, Weizhi, Zhan, Jun, Ma, Ji, Li, Xueying, Xie, Yuping, Wang, Jiadong, Zhu, Wei-guo, Luo, Jianyuan, Zhang, Hongquan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159546/
https://ncbi.nlm.nih.gov/pubmed/27613418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw808
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