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The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth

High-mobility group AT-hook 2 (HMGA2) is an architectural transcription factor that plays essential roles in embryonic development and cancer progression. However, the mechanism of HMGA2 regulation remains largely uncharacterized. Here, we demonstrate that HMGA2 can be modulated by hepatitis B X-int...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wu, Yue, Wang, Xue, Xu, Feifei, Zhang, Lu, Wang, Tianjiao, Fu, Xueli, Jin, Tianzhi, Zhang, Weiying, Ye, Lihong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229824/
https://ncbi.nlm.nih.gov/pubmed/32313942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa232
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