The transcriptional co-activator PCAF regulates cdk2 activity

Cyclin dependent kinases (cdks) regulate cell cycle progression and transcription. We report here that the transcriptional co-activator PCAF directly interacts with cdk2. This interaction is mainly produced during S and G(2)/M phases of the cell cycle. As a consequence of this association, PCAF inhi...

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Hlavní autoři: Mateo, Francesca, Vidal-Laliena, Miriam, Canela, Núria, Zecchin, Annalisa, Martínez-Balbás, Marian, Agell, Neus, Giacca, Mauro, Pujol, María Jesús, Bachs, Oriol
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790897/
https://ncbi.nlm.nih.gov/pubmed/19773423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp777
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