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Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs

Long non-coding RNAs (lncRNAs) are components of epigenetic control mechanisms that ensure appropriate and timely gene expression. The functions of lncRNAs are often mediated through associated gene regulatory activities, but how lncRNAs are distinguished from other RNAs and recruit effector complex...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Thillainadesan, Gobi, Xiao, Hua, Holla, Sahana, Dhakshnamoorthy, Jothy, Jenkins, Lisa M. Miller, Wheeler, David, Grewal, Shiv I. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229227/
https://ncbi.nlm.nih.gov/pubmed/32415063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16280-y
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