Enhancer of rudimentary cooperates with conserved RNA processing factors to promote meiotic mRNA decay and facultative heterochromatin assembly

Erh1, the fission yeast homolog of Enhancer of rudimentary, is implicated in meiotic mRNA elimination during vegetative growth, but its function is poorly understood. We show that Erh1 and the RNA-binding protein Mmi1 form a stoichiometric complex called EMC (Erh1-Mmi1 complex), to promote meiotic m...

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Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Sugiyama, Tomoyasu, Thillainadesan, Gobi, Chalamcharla, Venkata R., Meng, Zhaojing, Balachandran, Vanivilasini, Dhakshnamoorthy, Jothy, Zhou, Ming, Grewal, Shiv I.S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791967/
https://ncbi.nlm.nih.gov/pubmed/26942678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.029
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