Enhancer of rudimentary cooperates with conserved RNA processing factors to promote meiotic mRNA decay and facultative heterochromatin assembly

Erh1, the fission yeast homolog of Enhancer of rudimentary, is implicated in meiotic mRNA elimination during vegetative growth, but its function is poorly understood. We show that Erh1 and the RNA-binding protein Mmi1 form a stoichiometric complex called EMC (Erh1-Mmi1 complex), to promote meiotic m...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Sugiyama, Tomoyasu, Thillainadesan, Gobi, Chalamcharla, Venkata R., Meng, Zhaojing, Balachandran, Vanivilasini, Dhakshnamoorthy, Jothy, Zhou, Ming, Grewal, Shiv I.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791967/
https://ncbi.nlm.nih.gov/pubmed/26942678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.029
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