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Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 tri-methylation

Heterochromatin assembly requires methylation of histone H3 lysine 9 (H3K9me) and serves as a paradigm for understanding the importance of histone modifications in epigenetic genome control. Heterochromatin is nucleated at specific genomic sites and spreads across extended chromosomal domains to pro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cutter DiPiazza, Amber R., Taneja, Nitika, Dhakshnamoorthy, Jothy, Wheeler, David, Holla, Sahana, Grewal, Shiv I. S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179192/
https://ncbi.nlm.nih.gov/pubmed/34035174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100699118
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