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A single TRPV1 amino acid controls species sensitivity to capsaicin

Chili peppers produce capsaicin (a vanilloid) that activates the transient receptor potential cation channel subfamily V member 1 (TRPV1) on sensory neurons to alter their membrane potential and induce pain. To identify residues responsible for differential TRPV1 capsaicin sensitivity among species,...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chu, Ying, Cohen, Bruce E., Chuang, Huai-hu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229161/
https://ncbi.nlm.nih.gov/pubmed/32415171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64584-2
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