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Oxidative challenges sensitize the capsaicin receptor by covalent cysteine modification
The capsaicin receptor TRPV1, one of the major transduction channels in the pain pathway, integrates information from extracellular milieu to control excitability of primary nociceptive neurons. Sensitization of TRPV1 heightens pain sensation to moderately noxious or even innocuous stimuli. We repor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785298/ https://ncbi.nlm.nih.gov/pubmed/19897733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902675106 |
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